Percocet (oxycodone / acetaminophen) is a combination opioid medication. It's used to treat pain when non-opioid medications aren't working well enough to control pain. It's a controlled substance because it has a high risk of misuse, dependency, and addiction. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user. Includes Oxycodone and Acetaminophen indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Oxycodone acetaminophen is a prescription drug used for the management of moderate to severe pain. Learn about side effects, dosages, drug interactions, and more. Oxycodone/acetaminophen is a combination pain -relief (analgesic) medication prescribed to treat acute moderate-to-severe pain. Oxycodone is an opioid analgesic, while acetaminophen is a nonopioid drug that reduces pain and fever. Generic oxycodone/acetaminophen is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Get Oxycodone/Acetaminophen for as low as $17.26, which is 85% off the average retail price of $115.14 for the most common version, by using a GoodRx coupon. This guide compares prescription opioids (oxycodone and hydrocodone) against over-the-counter analgesics (acetaminophen, ibuprofen, and naproxen) across various pain conditions. Percocet (oxycodone and acetaminophen) is a combination drug consisting of an opioid and a pain reliever and fever reducer (analgesic and antipyretic) used for the management of moderate to severe pain, usually for an extended time period. Oxycodone and acetaminophen tablets are used to manage pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate, and when other pain treatments such as non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Oxycodone and acetaminophen combination can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong opioid pain medicines.