Oxycodone doesn’t have acetaminophen (Tylenol) in it, but Percocet does. Because of this acetaminophen component, Percocet can have additional (but rare) side effects, such as liver damage when used at high doses. Oxycodone and Acetaminophen Tablets package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Oxycodone and acetaminophen combination can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong opioid pain medicines. Oxycodone and acetaminophen tablets are used to manage pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate, and when other pain treatments such as non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Each oxycodone and acetaminophen tablet USP 7.5 mg/325 mg contains oxycodone hydrochloride 7.5 mg (equivalent to 6.7228 mg oxycodone) and acetaminophen 325 mg. It is available as a white to off-white caplet shaped tablet debossed with “M522” on one side and “7.5/325” on the other side. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user. Oxycodone acetaminophen is a prescription drug used for the management of moderate to severe pain. Learn about side effects, dosages, drug interactions, and more. When a patient who has been taking Oxycodone and Acetaminophen Tablets regularly and may be physically dependent no longer requires therapy with Oxycodone and Acetaminophen Tablets, use a gradual downward titration of the dosage to prevent signs and symptoms of withdrawal. ACETAMINOPHEN; OXYCODONE (a set a MEE noe fen; ox i KOE done) treats moderate pain. It is prescribed when other pain medications have not worked or cannot be tolerated. Oxycodone/acetaminophen is a combination pain -relief (analgesic) medication prescribed to treat acute moderate-to-severe pain. Oxycodone is an opioid analgesic, while acetaminophen is a nonopioid drug that reduces pain and fever.